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What you can expect from ZYFLO CR® (zileuton)

ZYFLO CR® is intended to help you get your asthma under control:

  • Clinical studies have shown that ZYFLO CR® significantly improves lung function in many patients, improving the ability to move air in and out of the lungs
  • It has also been shown to reduce rescue inhaler use

Not everyone will respond to ZYFLO CR® in the same way. After you start taking ZYFLO CR®, talk to your doctor about your asthma symptoms to determine if ZYFLO CR® is working for you.

Get medical help right away if you need to use your rescue medicine more often than usual or if you use the highest number of “puffs” prescribed for one 24-hour period. These could be signs that your asthma is getting worse. This means that your asthma therapy may need to be changed.

Warning, precautions and adverse reactions for ZYFLO CR®

Do not take ZYFLO CR® if you have active liver disease or repeated blood tests showing elevated liver enzymes (substances released by the liver), or if you have ever had an allergic reaction to ZYFLO CR® or any of the ingredients in ZYFLO CR®.

Before you start taking ZYFLO CR® you should talk to your health care provider if you have ever had liver problems, including hepatitis, jaundice (yellow eyes or skin), or dark urine. You should also tell your doctor if you drink alcohol, have difficulty swallowing pills, are pregnant or are planning to become pregnant, if you are breastfeeding, or about any other medicines you’re taking because there could be side effects.

Sleep disorders and changes in your behavior can happen while you take ZYFLO CR®. Tell your health care provider if you have any sleep problems or changes in behavior.

ZYFLO CR® may cause side effects in some people. Tell your health care provider right away if you get any of the following signs or symptoms:

  • Pain on the right side of your abdomen (stomach area)
  • Nausea
  • Tiredness
  • Lack of energy
  • Itching
  • Yellow skin or yellow color in the whites of your eyes
  • Dark urine
  • “Flu-like” symptoms

Some of the most common side effects are:

  • Nose and throat irritation
  • Sinusitis
  • Upper respiratory infection
  • Throat pain
  • Headache
  • Muscle aches
  • Nausea
  • Diarrhea

Even if you do not have any of these symptoms, continue to see your doctor for regular checkups and liver function monitoring.

Tell your doctor if you experience any new or unusual symptoms while taking ZYFLO CR®. Allergic reactions can happen while taking ZYFLO CR®. Tell your doctor right away if you get a rash or hives.

ZYFLO CR® is a medicine that is used to prevent asthma attacks and for long-term management of asthma in adults and children 12 years of age and older.

ZYFLO CR® is not a rescue medicine and should not be used if you need relief right away for an asthma attack. However, you can continue taking your regularly scheduled dose of ZYFLO CR® during an asthma attack.

*See ZYFLO connect® Terms and Conditions