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Prescribe ZYFLO CR® (zileuton) as an alternative for the prophylaxis and chronic treatment of asthma

Adapted from the National Heart, Lung, and Blood Institute (NHLBI): Guidelines for the Diagnosis and Management of Asthma. 2007.
  • ZYFLO CR® is recommended as an alternative due to limited studies as adjunctive therapy and the need to monitor liver function¹
  • ZYFLO CR® is indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older. Do not use ZYFLO CR® to treat an acute asthma attack.
  • ZYFLO CR® is contraindicated for patients with active liver disease or persistent hepatic function enzyme elevations ≤3 times the upper limit of normal. ZYFLO CR® is also contraindicated for patients with a history of allergic reactions to zileuton or any of the other ingredients.

Please see Important Safety Information and Full Prescribing Information.

*See ZYFLO connect® Terms and Conditions

Reference: 1. Guidelines for the Diagnosis and Management of Asthma. July 2007. National Heart, Lung, and Blood Institute Web site: http://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines. Accessed January 9, 2009.